Antidepressants play a crucial role in managing depression, but new research suggests they may also contribute to weight gain.
A Spanish study, published in Frontiers in Psychiatry, tracked over 3,000 adults for six years and found that individuals using antidepressants experienced an average two per cent increase in body weight.
Link between depression and weight
Depression and obesity share a complicated relationship. While depression can lead to weight gain, obesity also increases the risk of depression. Many antidepressants, though effective in managing mental health, have been linked to weight changes, with long-term use showing a stronger correlation.
Study insights: tracking weight changes over time
Researchers analyzed data from the Girona Heart Registry, categorizing participants into four groups based on antidepressant use: never used, stopped before follow-up, started later, and continuous users.
Even after adjusting for factors like age, sex, and lifestyle, those who used antidepressants—regardless of duration—were more likely to gain weight.
Who is most affected?
Women, individuals under 55, and those initially at a healthy weight were more prone to significant weight gain. Continuous users faced a higher risk of obesity by the study’s end.
Implications for treatment
Experts stress the need for a holistic approach to antidepressant prescriptions. Certain medications, like mirtazapine and paroxetine, are more likely to cause weight gain, making it essential to consider alternative treatments.
While antidepressants remain vital, patients should monitor their weight and discuss strategies like diet and exercise with their doctors.
Future research aims to analyze specific medications and their impact, helping patients make informed choices for both mental and physical well-being.
Source: Hindustan Times
Bd-pratidin English/Fariha Nowshin Chinika
