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US Secretary of State Antony Blinken is meeting leaders from Lebanon, Qatar and Jordan in Amman as UN says 'no safe places in Gaza'.
Blinken will also hold discussions with foreign ministers from Saudi Arabia, Egypt and the UAE.
Visiting Israel on Friday, he called for humanitarian pauses in the fighting in Gaza, as warnings about the dire situation there mount, reports BBC.
The US secretary of state will also hold a meeting with UN Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) commissioner general Phillipe Lazzarini and a video call with his Gaza-based staff.
But Israeli PM Benjamin Netanyahu said there will be no temporary ceasefire with Hamas in Gaza until all Israeli hostages are released.
There is increasingly little the United Nations can do to protect Gazans, an official from the UN agency for Palestinian refugees has warned.
On the ground, Israel said it had struck an ambulance in Gaza it said was being used by Hamas operatives.
The Palestinian Red Crescent Society said 15 were killed when an ambulance was hit outside al-Shifa hospital in Gaza City.
Bd-pratidin English/Golam Rosul
