More strikes have been reported across Ukraine including a gas production plant in the east and a missile factory in Dnipro, days after one of Russia's most intense bombardments of the war.
Parts of Ukraine have seen their first snowfall of the season, but many people cannot heat their homes as Russia continues to pound their power grid early on Thursday, reports BBC.
One of Ukraine's largest cities, Dnipro, was among those targeted. Prime Minister Denys Shmyhal said the Pivdenmash factory - which produces missiles - had come under attack.
Another official said 14 people, including a teenager, had been taken to hospital after the city was shelled.
Elsewhere in the same region, 70 shells were said to have landed around the city of Nikopol, damaging infrastructure and leaving thousands of homes without power and water.
State-owned energy firm Naftogaz said its gas-producing facilities in the east of the country had been subjected to a "massive attack".
In its nationwide update, the president's office said four people died as a result of an overnight strike on residential buildings in the Zaporizhzhia region.
Russia has looked to justify its recent strikes by accusing Kyiv of "unwillingness" to negotiate.
Bd-pratidin English/Golam Rosul